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Help, nothing compatible

HR and OH departments – how to work with them to achieve the best results

Understanding your laboratories baseline data is the most important first step to identify where to improve services. Data is key to understanding preanalytical processes, simple things such as the location of phlebotomy clinics, the timings of transport collections, the number of paper requests all have an impact on specimen reception workflows and specimen turnaround times.

Many labs still continue to measure a specimen's turnaround time from the moment it arrives at the lab, which is too late.

We will demonstrate how data modelling and innovative transport solutions will improve system workflows, reduce specimen rejections, smooth out specimen arrivals, reduce the output of CO2 and meet the preanalytical quality requirements for your next UKAS inspection.

Explanation of the various serological and molecular techniques that are available to identify novel blood groups. Discussing how these cases may present within the hospital and RCI labortories through to publication and ratification at the International Society of Blood Transfusion.

It’s life, but not as we know it. Emerging parasitic diseases

If you're interested in blood groups, blood group serology, transfusion or just want to know "what the hell is Kell?" then this talk is for you...

This presentation on the Kell Blood group system will cover the following;

An entertaining overview of the Kell blood group system
Structure, function and molecular background of the most well-known Kell blood group system antigens
Clinical significance of antibodies to Kell blood group system antigens
The association with the Kx blood group system
Interesting facts about the lesser known Kell Blood group system antigens

In 2022 the unthinkable happened - NHSBT was forced to declare an Amber Alert for red cells in England. But does that tell the whole story? This presentation will briefly examine the build-up to the shortage declaration but also consider its impact, provide evidence of the response within hospitals and consider the opportunities for future change in practices.

Managing change with compassion

To explore the molecular profiles of Acanthamoeba from laboratory-confirmed Acanthamoeba keratitis (AK) cases reported within the United Kingdom (UK) using DNA taken directly from clinical samples.

Acanthamoeba species are free-living organisms responsible for causing a debilitating, sight-threatening disease of the cornea. Of the 24 known Acanthamoeba species, 14 cause AK.

Thirty-five Acanthamoeba DNA-positive corneal samples from the Scottish Microbiology Reference Laboratories (SMiRL), Glasgow collection were selected from cases reported from 2017 - 2019. Following extraction of the DNA directly from each clinical specimen, the DNA was subjected to in-depth molecular typing using a nested PCR / bi-directional sequencing approach.

Molecular profiling was successful for 32 samples which comprised of two genotypes namely T3 and T4. The T4 genotype were further sub-typed; five sub-types existed namely; T4A, T4B, T4C, T4E and T4F.

Using a molecular typing assay applied directly to corneal tissue, this study highlights the T4 genotype and the T4A subtype are the predominant molecular variants of Acanthamoeba to cause ocular disease in the UK. Gaining in-depth information on the molecular profiling of Acanthamoeba is essential to increase our knowledge and understanding of the epidemiology, transmission pathways and potential associations with clinical outcomes for this rare, yet potentially debilitating ocular disease.

Monkeypox case management/infection control