CONGRESS 2023 - Can a laboratory investigate allergic reactions to COVID vaccines?
Vaccinations to Covid 19 virus have been at the forefront of news headlines. One of the issues highlighted was the risk of adverse reactions, both allergic and non-allergic. This caused an influx of queries to Allergy services regarding patients who had suffered potential allergic reactions and posed the question, 'how can they be investigated'? The laboratory has limited commercial assays to the components and excipients of vaccines. However, tests can potentially be modified or developed in-house to provide evidence of a potential allergy. They could also be utilised to determine if an alternative vaccination can be used. The testing strategy may need to be adapted on a case by case basis. There is the potential that this could be used to develop a service for allergic reaction investigation for all vaccine types.
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Learning Outcomes
Delegates will gain knowledge of:
- The components of vaccines that can be allergenic.
- What laboratory investigations can be performed to determine if an adverse reaction was IgE mediated and how these can be adapted to investigate vaccine responses.
- Whether these investigations be used to determine if alternative vaccines can be given to the individual?
- Apply this information to case presentations to show how the investigations can be adapted depending on the questions that need to be answered for the patient.
- Potential further tests that can be introduced to aid in investigating adverse reactions to vaccines.