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CONGRESS 2023 - Resuscitation with Pre-Hospital Blood Products (RePHILL) trial

Resuscitation with Pre-Hospital Blood Products (RePHILL) trial

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28th September 2023
Venue: The International Convention Centre (ICC), Birmingham
Learning outcomes

RePHILL (Resuscitation with Pre-Hospital Blood Products) was a multi-centre randomised controlled trial of pre-hospital blood product administration versus standard care for traumatic haemorrhage, funded by the National Institute for Health Research (NIHR) Efficacy & Mechanism Evaluation Programme.

The trial tested the hypothesis that Pre-Hospital Blood Products (PHBP) resuscitation with up to two units each of packed red blood cells (PRBC) and lyophilised plasma (LyoPlas N-w) will improve tissue perfusion (as measured by lactate clearance) and reduce mortality in trauma patients with haemorrhagic shock compared to the current standard practice of crystalloid (normal saline) resuscitation. This presentation will explore the outcomes of the trial.