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This cases study focusses on a paient that showed dual positivity for Anti-GBM and Anti-PLA2r antibodies. It will look at how testing was requested, the methods used for the investigations and how the results lead to the conclusions drawn.

It will also look at testing algorithms in the Immunology laboratory, related to these investigations and how these could be improved.

The analysis of free light chains in clinical laboratories to support the diagnosis and treatment monitoring of Myeloma has evolved over 6 decades. From urine analysis for Bence Jones Protein using gel electrophoresis in the 1950s to the launch of the first commercial assay for serum free light chain measurement in 2001.

This talk will describe the biochemistry of free light chains and the benefits and challenges of the different methodologies available in laboratories today. I will also describe the complexity of clinical interpretation of results, highlighting relevant national guidance, recently developed diagnostic tools for clinicians and testing advice for laboratories.

A role with a difference – anatomical pathology technologist in a mortuary

Albert Norman Keynote Opening Address

AMR/CSO Diagnostic pathway change – Biomedical Scientist Perspective

Bench to Bedside: Clinical Cases from an HSST

Defining biomedical scientists in the NHS Long Term Workforce Plan - the IBMS plan

Eco-epidemiology of tick-borne encephalitis virus in the UK

Globally, arthropod-borne viral diseases represent one the of greatest threats to public and animal health. Vectors such as mosquitoes, ticks and midges transmit a vast range of viruses. For the UK, historically free of many arthropod-borne pathogens, events in mainland Europe have had a profound impact on the risk of disease emergence and this trend will continue. Mosquito-borne viruses provide an example of this process where the introduction of exotic species, such as the Asian tiger mosquito (Aedes albopictus) across much of Europe, has increased the risk of emergence of human pathogens such as dengue and chikungunya fever. This mosquito species has also been detected in southern England.

In recent decades there has been a dramatic increase in the distribution of zoonotic viruses such as West Nile and Usutu in mainland Europe that are making the introduction of these pathogens through short distance bird migration increasingly likely. This has been realised with the repeated detection of Usutu virus in Central London during the late summer months since 2020. In the absence of vaccines against many of these viruses, early detection linked to public awareness campaigns offer the best options for mitigating the impact of these threats.

EQA of Autoimmunity