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CONGRESS 2023 - Pathogen detection & chronic lung infection underestimated in cystic fibrosis

Chronic lung infection is the leading cause of morbidity and early mortality for people with cystic fibrosis (pwCF). Microbiological surveillance to detect lung pathogens is recommended as best practise in CF patient care. Here we studied pathogen detection in forty pwCF over several years. We found that microbiological culture, the diagnostic gold standard, was significantly disparate to targeted culture-independent approaches for detection and determination of chronic infection status of two important pathogens in CF. Pathogen detection was significantly lower by culture and consequently infection status was also misclassified in the majority of cases.

In particular, the extent of chronic infection by both Pseudomonas aeruginosa and Staphylococcus aureus not realised with culture was striking. Our findings have implications for the development of infection and clinical care of pwCF. Future longitudinal studies with greater patient numbers will be needed to establish the full extent of the clinical implications indicated from this study.

CONGRESS 2023 - Pets to pandemics – viral zoonoses

It is clear that the interaction of humans with animals and the environment has been at the centre of infectious disease emergence and spread through out history. Recent global events have shown that this is still the case, or at least likely to be! Close contact with animals and our collective movements in and out of each others environments has the potential to permit transmission of organisms that have the potential to cause zoonotic or indeed enzoonotic disease. We need to consider this aspect carefully to understand what mitigations we might need to put into place and also what considerations might need to be taken on board in the light of changes to infection patterns as a possible consequence of climate change.

CONGRESS 2023 - Point-of-Care Testing in the community

To introduce a discovery community Point of Care Testing project that is working collaboratively with primary and secondary care.

By working in wider partnerships, the project aims are to scope and work towards recommendations and collaboration to deliver effective and measurable benefits for safer patient care and a governance led service, aligned to national NHS strategy plans.

CONGRESS 2023 - Quality in IT Procurement (Thursday)

Quality in IT Procurement

CONGRESS 2023 - RCI – the Biomedical Scientist role

An overview of Red Cell Immunohaematology (RCI), the services offered and how we fit in within the wider healthcare system.

Example cases starting with single specificity through to complex antibody identification using a variety of techniques. Discussing the need for consultant input when serology cannot be resolved and what happens next.

We will briefly cover duties beyond serology performed as a biomedical scientist and how these fit in nationally as well as locally.

Finishing on the progression routes through RCI, NHSBT and the wider transfusion community.

CONGRESS 2023 - Resuscitation with Pre-Hospital Blood Products (RePHILL) trial

Resuscitation with Pre-Hospital Blood Products (RePHILL) trial

CONGRESS 2023 - Rudeness costs lives

Many reports have demonstrated the correlation between good team working and better outcomes. This talk explores the value of civility and the cost to our patients of rudeness in the workplace.

CONGRESS 2023 - Shiga toxin-producing Escherichia coli O26 (STEC O26)

Shiga toxin-producing Escherichia coli (STEC) O157:H7 has been the most clinically significant STEC serotype in the UK for over four decades. However, over the last 10 years we have observed a decrease in STEC O157:H7 and an increase in non-O157 STEC serotypes, such as O26:H11. Little is known about the microbiology and epidemiology of non-O157 STEC. This presentation describes the virulence, clinical outcomes and epidemiology of non-O157 STEC, focusing on the most commonly detected serotype, STEC O26:H11.

CONGRESS 2023 - Supporting Point-of-Care Testing in Virtual Wards: What are the challenges and how do we overcome them?

A variety of virtual ward services are delivered across Oxfordshire through collaboration of Oxford University Hospitals NHS Foundation Trust, Oxford Health NHS Foundation Trust, and Principal Medical Ltd (PML) a GP led service. They include Hospital at Home, Children’s Virtual Ward (jointly with OHFT), Acute & Community Palliative/End of Life Care (Community – Sue Ryder Care).

The Point of Care Testing (PoCT) team at Oxford University Hospitals NHS Trust has supported the development and delivery of PoCT in community and ambulatory settings over the past 10 years.

Using a model developed around the requirements of ambulatory medicine; this has been delivered with limited resource, focussing on utilising existing resources wherever possible.

Commencing with the Acute Hospital at Home, the service has been successfully expanded to support mobile PoCT across Oxfordshire.

The laboratory acts as the distributor of instruments and supplies; facilitates connectivity, and testing, and coordinates delivery of training through a combination of remote and cascade routes.

Device selection and repertoire has been standardised. Up to this point mobile services have been limited to use of the Abbott i-Stat & Alinity systems (electrolytes/metabolites/blood gas). However, Hospital at Home, and other mobile services are requesting a greater repertoire of tests, particularly CRP. The LumiraDx platform provides us with an option for CRP that is portable, easy to operate, connectable and robust.

Challenges remain around connectivity and information management. This has been exacerbated by the cross-organisational nature of these services leading to the management of patients through multiple IT systems; and led to the development of indirect routes for result entry into the patient record.

Whilst we have been able to deliver connectivity in two rapid response vehicles, this was not a scalable solution and mobile devices are docked at the base location on return from visits.

CONGRESS 2023 - The IBMS's view of ISO 15189:2022 (Thursday)

The IBMS's view of ISO 15189:2022
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