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CONGRESS 2023 - Managing change with compassion

Managing change with compassion

CONGRESS 2023 - Molecular Profiling of Acanthamoeba species directly from Ocular Tissue

To explore the molecular profiles of Acanthamoeba from laboratory-confirmed Acanthamoeba keratitis (AK) cases reported within the United Kingdom (UK) using DNA taken directly from clinical samples.

Acanthamoeba species are free-living organisms responsible for causing a debilitating, sight-threatening disease of the cornea. Of the 24 known Acanthamoeba species, 14 cause AK.

Thirty-five Acanthamoeba DNA-positive corneal samples from the Scottish Microbiology Reference Laboratories (SMiRL), Glasgow collection were selected from cases reported from 2017 - 2019. Following extraction of the DNA directly from each clinical specimen, the DNA was subjected to in-depth molecular typing using a nested PCR / bi-directional sequencing approach.

Molecular profiling was successful for 32 samples which comprised of two genotypes namely T3 and T4. The T4 genotype were further sub-typed; five sub-types existed namely; T4A, T4B, T4C, T4E and T4F.

Using a molecular typing assay applied directly to corneal tissue, this study highlights the T4 genotype and the T4A subtype are the predominant molecular variants of Acanthamoeba to cause ocular disease in the UK. Gaining in-depth information on the molecular profiling of Acanthamoeba is essential to increase our knowledge and understanding of the epidemiology, transmission pathways and potential associations with clinical outcomes for this rare, yet potentially debilitating ocular disease.

CONGRESS 2023 - Monkeypox case management/infection control

Monkeypox case management/infection control

CONGRESS 2023 - My early career Point-of-Care Testing experience

This presentation will include how her career progressed to a Point of Care Testing (POCT) role in the Wales Specialist Virology Centre. It will also cover what POCT is; the method of testing, who gets tested and why POCT is crucial in the efforts to achieve the WHO initiative to eliminate Hepatitis C in Wales.

Examples of what a day-in-the-life of a "POCT-er" consists of: mass screening projects, case studies, what has been learnt from testing in prison and in the community (homeless shelters and substance misuse services). The future of POCT: what's on the horizon?

CONGRESS 2023 - Near-patient testing - (self-collected samples; breath test to bloods)

The presentation provides an overview on potential benefits and risks of near-patient testing conducted by health care professionals, including testing of self-collected specimens.

CONGRESS 2023 - Neonatal Meningitis

This presentation will outline the content of Paola's Clincal Case Study from her Higher Specialist Portfolio in Medical Microbiology. Here she will present the initial clinical presentation, diagnosis and treatment of a case of neonatal sepsis that linked to a previous unusual maternal screening swab. She will also outline her experience of the Higher Specialist Diploma and her plans for developing a training plan within Microbiology QMC, Nottingham for future candidates within their trust.

CONGRESS 2023 - Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR

Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR

CONGRESS 2023 - Nuisance Antibodies

Nuisance Antibodies

CONGRESS 2023 - Performance of a new molecular Point-of-Care system for respiratory viruses under field conditions

The presentation provides an overview on the technology and analytical performance of a new true molecular point of care testing system without need for upfront specimen preparation, and the potential benefits resulting from its use at the point of care. The presentation also discusses key aspects to be considered prior to implementation at the point of care

CONGRESS 2023 - Polio – why has it reappeared?

Polio – why has it reappeared?
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