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CONGRESS 2023 - Meet your Haematology Portfolio examiners

27/09/2023
Meet your Haematology Portfolio examiners

CONGRESS 2023 - Myeloma screening – Best practice and new developments

27/09/2023
Myeloma screening is a high volume investigation pathway, performed by both Biochemsitry and Immunology laboratories. National audit data has shown there to be high variation between laboratories on the implementation of this workflow, leading to potentially inconsistent patient care geographically.

This talk will aim to cover the following areas:

Give brief foundation knowledge on serum electrophoresis/immunodisplacement/immunofixation
Introduce the Myeloma UK Best practice guidelines for Myeloma screening
Discuss Mass spec methods for analysing monoclonal protein
Discuss monitoring of myeloma patients and monitoring of Monoclonal gammopathy of undetermined significance (MGUS) patients.

CONGRESS 2023 - Myositis antibodies: are we missing something?

27/09/2023
A myositis-related autoantibody can now be identified in the majority of patients with myositis. They identify homogeneous patient subgroups and are key tools in developing a personalised approach to disease management. There is substantial clinical interest in exploiting myositis autoantibodies as biomarkers, and consequently, a large number of commercial assays have been developed for their detection. Several different commercial assays have now been developed to detect myositis relevant autoantibodies. Many have been developed with the practicalities of clinical practice in mind, offering rapid, affordable, and often multiplex testing. Despite this progress, the perfect system has yet to be realised.

Commercial testing systems do not detect all known myositis relevant autoantibodies and concerns have been raised about the sensitivity and specificity of some assays, including to their ability detect some autoantibodies strongly associated with malignancy and ILD; important causes of mortality and morbidity.

The advantages and disadvantages of different myositis autoantibody testing systems will be discussed. Evidence for the reliability of different types of assays in comparison to immunoprecipitation, as the reference standard, will be reviewed along with testing strategies that make the most of existing technology.

CONGRESS 2023 - Narcolepsy and its association with HLA type

26/09/2023
This presentation will introduce basic sleep physiology related to the pathophysiological mechanisms Narcolepsy is a rare but debilitating neurological sleep disorder, with a worldwide prevalence of 25-50 per 100,000 people. Onset is most common during the adolescent years, though a diagnostic delay of around 10 years is common. There is currently no cure, though symptoms can be managed using pharmacotherapy. Biochemistry services provide an important role in confirming a diagnosis of narcolepsy in line with current international guidelines such as the International Classification of Sleep Disorders 3rd edition (ICSD-3).

The aims of this talk are to:

1. Introduce basic sleep physiology related to the pathophysiological mechanisms underpinning narcolepsy.

2. To describe the signs and symptoms of narcolepsy and their impact on patients.

3. To review the diagnosis of narcolepsy including the role of biomarkers such as HLA type and CSF hypocretin.

4. To summarise treatment options for narcolepsy.

CONGRESS 2023 - Networks – how Greater Manchester is making it work for them

27/09/2023
Networks – how Greater Manchester is making it work for them

CONGRESS 2023 - Overview and Escalation of EQA

27/09/2023
Overview of Governance and Escalation of Persistent Poor Performers," we will be discussing the governance structure of EQA in the UK, as well as poor performance and escalation. We will provide three examples and encourage audience participation

CONGRESS 2023 - Peanut Immunotherapy - theory and practice within the NHS

27/09/2023
Food-induced immunotherapy has been practiced with varying success for over 100 years. Over the past 10 - 15 years it has gained a greater recognition in the potential management of children with food allergies. Food-induced immunotherapy can take the form of oral, epicutaneous or sublingual routes and usually results in a short-lived desensitisation rather than the acquisition of tolerance. For this reason, food immunotherapy is not a cure but relies on regular, usually daily, ingestion. Peanut immunotherapy lies mainly within the domain of clinic research however Palforzia (roasted peanut flour), was approved by NICE in February 2022 for the management of peanut allergy in children 4 to 17 years of age. The methodologies and factors associated with successful desensitisation to peanut will be discussed.

CONGRESS 2023 - Quality issues and accreditation for andrology services

26/09/2023
Quality issues and accreditation for andrology services

CONGRESS 2023 - Returning to practice – everything you need to know

28/09/2023
This presentation will explain the Health and Care Professions Council (HCPC) return to practice process and the support offered by NHS England’s National Return to Practice programme to return skilled professionals back into the NHS workforce.

This presentation will cover the below content:

HCPC requirements to return to the register
Routes to returning to the HCPC register
NHS England’s Return to Practice programme support to returners and organisations and systems
Returner registration on the NHS England Return to Practice programme
Considerations for organisations wanting to support a returner to practice.

CONGRESS 2023 - Review of malaria rapid tests

26/09/2023
Rapid antigen tests for malaria have been in routine use in UK haematology labs for many years now. However, interpretation of their results, especially in light of the accompanying blood film findings can still prove to be confusing.

The advantages and limitations of these tests will be explored and explained.
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